HATU – CAS # 148893-10-1

HATU plays a crucial role in peptide synthesis by activating carboxylic acids and facilitating the peptide coupling reaction with amino acids or peptide fragments. Its unique structure and reactivity enable efficient peptide bond formation, resulting in the production of high-quality peptides.

One of the notable advantages of using HATU is its compatibility with a wide range of amino acid derivatives and protecting groups. This versatility allows for the synthesis of complex peptides with specific modifications and functionalities.

HATU offers several benefits over other commonly used coupling reagents. It exhibits superior solubility in common organic solvents, making it easy to handle and dissolve in reaction mixtures. It also reduces the formation of unwanted byproducts and side reactions, leading to improved reaction yields and overall efficiency.

Moreover, HATU is known for its stability and long shelf life, making it a reliable reagent for peptide synthesis and other organic transformations.

It is important to handle HATU with caution, as it can cause skin and eye irritation. Personal protective equipment, such as gloves and goggles, should be worn when working with it to minimize the risk of exposure. Adequate ventilation in the working area is recommended to prevent the buildup of vapors.

In conclusion, HATU (CAS 148893-10-1) is a highly efficient coupling reagent extensively used in peptide synthesis and organic chemistry. Its ability to activate carboxylic acids and promote rapid peptide bond formation makes it a valuable tool in the production of high-quality peptides. With proper handling and safety measures, HATU offers improved yields, compatibility with various amino acid derivatives, and enhanced overall efficiency in peptide synthesis.